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The Inflammation Cure: Simple Steps for Reversing Heart Disease, Arthritis, Diabetes, Asthma, Alzheimer's Disease, Osteoporosis, Other Diseases of Aging

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In addition to explaining inflammation's causes and its role in various diseases, the author offers advice--'an antiinflammation game plan'--on how to maintain 'inflammation balance' and feel better.--The New York Times In clear, everyday language, William Meggs, M.D., explains what causes inflammation, its relationship to disease in the body, and what steps readers can tak In addition to explaining inflammation's causes and its role in various diseases, the author offers advice--'an antiinflammation game plan'--on how to maintain 'inflammation balance' and feel better.--The New York Times In clear, everyday language, William Meggs, M.D., explains what causes inflammation, its relationship to disease in the body, and what steps readers can take to minimize their risk.


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In addition to explaining inflammation's causes and its role in various diseases, the author offers advice--'an antiinflammation game plan'--on how to maintain 'inflammation balance' and feel better.--The New York Times In clear, everyday language, William Meggs, M.D., explains what causes inflammation, its relationship to disease in the body, and what steps readers can tak In addition to explaining inflammation's causes and its role in various diseases, the author offers advice--'an antiinflammation game plan'--on how to maintain 'inflammation balance' and feel better.--The New York Times In clear, everyday language, William Meggs, M.D., explains what causes inflammation, its relationship to disease in the body, and what steps readers can take to minimize their risk.

30 review for The Inflammation Cure: Simple Steps for Reversing Heart Disease, Arthritis, Diabetes, Asthma, Alzheimer's Disease, Osteoporosis, Other Diseases of Aging

  1. 4 out of 5

    Glenda

    Read this book a long time ago and found the notes on computer. The Inflammation Cure How to Combat the Hidden Factor in …. By Dr William Joel Meggs, MD Factor x is somehow related to factor y…..people with inflammation of the gums are at greater risk for of having artherosclerosis – walls of arteries full of plaque… Peridontal disease is related to diabetes….also to preterm delivery…. Oral hygiene – greater priority…. Groups of people who need to take immediate action to control inflammation. 1. Anyon Read this book a long time ago and found the notes on computer. The Inflammation Cure How to Combat the Hidden Factor in …. By Dr William Joel Meggs, MD Factor x is somehow related to factor y…..people with inflammation of the gums are at greater risk for of having artherosclerosis – walls of arteries full of plaque… Peridontal disease is related to diabetes….also to preterm delivery…. Oral hygiene – greater priority…. Groups of people who need to take immediate action to control inflammation. 1. Anyone with high cholesterol, high blood pressure, heart disease…. 2. Diabetes - type 1 – caused by autoimmune inflammatory reaction…. .type 2 ….prevented by controlling inflammation …. 3. Overweight - fat cells produce inflammatory chemicals…. 4. Family history of heart disease, stroke, diabetes, Alzheimers….trigger factor…. 5. Autoimmune disorder….rheumatoid arthritis, lupus, multiple sclerosis….. out-of-control inflammation reactions….Sjogren;s syndrome --- risk of autoimmune thyroid disease…. 6. Inflamed gums or periodontal disease…..inflamed liver cells,…. gums most visible indicator of an inflammation imbalance in our bodies …….psychological stress…. 7. Anyone feels tired or fatiqued all the time…. 8. Anyone over the age of 40…. 9. Anyone who works in an anti-infammatory environment….sick building, etc 10. Anyone suffering from depression or anxiety…..systematic lupis erythematosis SLE ..pattern of inflammation affecting joints, skin, and other organs….criteria….prior episode of depression or psychosis…..inflammation of the brain….strong association between allergy and depression… connection between overweight and asthma….(???or vice versa) Pg 11 explains inflammation Chpt 2 The Body’s Alarm System……compares the immune system to a fire alarm system….pain closely related to inflammation….poking for potential sites of inflammation…. Inflammation triggered by immune system and nervous system….immune system….stores a “most wanted” list of dangerous proteins…cause release of chemicals that cause neurogenic inflammation….sensory nerve C-fibers ….OR …emotional stress signaled from the nervous system.. Inflammation changes 1st. -- diameter of blood vessels increases to draw blood to the area…appears red and feels warm…….Inflammed skin turns white when touched…. 2nd vessels become leaky……wall cell shrink…..fluid swells tissue causing pressure and pain…. Case history: capillary leak syndrome….all over body capillaries leak…entire body swell…blood pressure dropped into range of cardiovascular shock…patient noticed that the leak occurred when she ate pork….inflammation reaction to pork. Pg 18 Bad cases of inflammation….blood vessels themselves become inflamed….leakage is so bad that big blood cells leak…pressure will not force the red blood cells away…nonblanching rashes – sign that dangerous disease is imminent…ex: vasculitis (inflammation of the blood vessels) or meningococcal sepsis (severe bacterial infection) 3rd effect: fluids can ooze from inflamed tissues into body cavities….thin, white, watery fluid (as in a blister), ….thick white fluid (pus) contains white blood cells…. Immune system failure….AIDS..virus…appetite for cells that control the immune system…..missing even a tiny piece of the immune response lead to system malfunction… Ex: a dozen proteins ….complement proteins……activated in sequence to form a large protein structure called the membrane attack complex- looks like a tube….attaches to surface of invading cells and punches holes in them…water rushes into holes and cells swell up and burst…missing just one of these means the complex can’t form properly ….fall ill to bacterial infections…. Malfunctions – body tricked or confused….2 examples: autoimmune and allergies….specialized cells ask each cell they encounter: are you self or other, friend or foe: …if the asked cell does not have password, they are attacked… Sometimes password breaks down…immune cells mistake body cells for intruders…ex: myelin sheaths surrounding nerve cells…..multiple sclerosis develops…. Allergies – immune system overreacts …..chemical sensitivity – example of nervous system overreacting…..inhaled pollen is treated like germs…. Site Switching - inflammation can have multiple effects all over the body…. Ex: 1. gonorrhea attacks genitals, but can inflame joints (no infection)…. …2..woman referred for bite of brown recluse spider…also being treated for boil on buttocks…It is possible for an inflammatory disorder at one site to produce one or more sores on the skin in another site…..infections, tumors, inflammatory bowel disease…. Boil on the butt had made a sore on the hand…. Case of site swiching named Sweet’s Syndrome after a British dermatologist described it….. Site Switching is very common in allergy and chemical sensitivity. Systemic anaphylaxis (allergy shock) – entire body allergic reaction ….histamine…released and attaches to nerves …send a signal to brain…sends out alarm out to entire body….nerves all the body release Substance P ….release more histamine… Scientists believe that whenever you have an insult to the body in one location and it produces inflammation in another location, this type of neurogenic switching is involved…..basis for inflammation connections among so many different diseases…. Tissue repair can be considered the tail end of inflammation. ……wound repair…..lymphocytes (type of white blood cell) release growth factors to begin …..other white blood cells (monocytes) change into macrophatges…clean up dead cells…. 2 kinds of cells – endothelial cells and fibroblasts – grow, divide, fill up holes….result is a scar… Healing, too, can malfunction…scar tissue can fill up a hole and continue thru whole body……..ex: scleroderma….normal body tissue is replace with scar tissue …skin, lungs, and organs become hard…. Ex: elderly woman….severe pain in arms and legs…fell and bruised left thigh….rock-hard object in muscle of her thigh….muscle had turned to bone….”Myositis Ossificans” …..extremely painful…resolves spontaneously…. Examples of where inflammation causes permanent changes: 1. People with severe, untreated asthma can have airway remodeling – actual physical structure of the lung changes in respond to repeated damage. 2. inflammation causes the growth of new blood vessels…contribute to cancer, psoriasis… 3. ageing itself …balance of inflammation and anti-inflammation upset… pg. 44 Connections People with gum disease are known to have a higher risk of cardiovascular heart disease. It may be that the infection that causes gum disease is enough to trigger the kind of inflammation that is associated with heart disease…or it may be that low-grade inflammation that is associated with heart disease may mean a change in the immune response, which allow germs in the mouth to do damage to the gums…… Gum disease is also related to diabetes……treating diabetics with gum disease helps them contol their blood sugar better…..chronic inflammation in the mouth can affect the whole body…… Ch 5 pg 47 Cancer Most common cancers all linked to inflammation….right set of circumstances…….some cases inflammation causes cancer, other it causes it to spread, some it can attack and kill small cancers…. Cancer develops slowly….occurs in 3 main stages….1st something changes normal cells to precancerous cells….may undergo 10 or more mutations before the change…. Reasons – chronic irritation, exposure to chemicals, virus, environmental damage, aging…….. 2nd promotion….cell multiplies….additional assaults…. Ex: Barrett’s esophagus….heartburn symptoms so severe that precancerous mutate in cells lining the esophagus…. 3rd progression…. Multiplying and spreading Cancers grow in a bed of normal cells called a stroma, support and nourishment for it…..camouflage of normalcy…..barrier against the immune cells….but when get too large it needs its own blood supply…..(1 milimeter) ..can stop and die….OR…releases chemicals that make new blood vessels (angiogenesis) and they attach to the body’s existing circulatory system….. Example where protective chemicals help the tumor instead: 1. Early stages of malignant skin cancer (melanoma) ainterleukin-6 (IL-6) can stop cancer growth, but very mature melanoma cells produce their own causing the cancer to grow… 2. macrophages……supposed to destroy the invader….some reason they become part of the stroma and help tumor to grow… Any assult on the body – long term inflammation….capable of becoming cancer….chronic viral or bacterial infection, mechanical or chemical irritation……. Short term inflammation ….heal wounds…destroy invaders….helps protect us from all diseases……..but scales tip into a constant state of inflammation… Ex: Heliobacter pylori…..stomach ulcers….very common bacteria… Uninary tract infections….linked to cancer of bladder…. Cancer associated with infection to viruses…..hepatitis B and hepatitis C…liver cancer……Epstein-Barr virus……mononucleosis…linked to lymphoma Strains of papillomaviruses…genital warts….cervical cancer… Mechanical or Chemical Irritation……erosion in the body….ex: esophagus is burned by digestive chemicals…….continual rubbing of an object….kidney stones…greater risk of cancer of kidney….. Disease inflammation….ex: ulcerative colitis…inflammatory disease of colon….risk of colon cancer…… If taking an anti-inflammatory medication reduces the risk of a disease then an inflammatory component must be assumed. Ex; women with rheumatoid arthritis developed breast cancer at lower rates…. Colon Cancer…..inflammation affects 1st IBD (long term inflammation) causes cellular mutations 2nd bacteria play a role…..population kept in check by immune system…… .severity and duration of inflammation Take aspirin or anti-inflammatory reduce risk of colon cancer by 40 to 50 %…act by suppressing COX2 …….300 mg aspirin each day for 6 months ….. Familial adenomatous polyposis—prone to develp polyps in colon…..anti-inflammatory med celecoxib reduced the size and number of polyps ….. Bacteria H. Pylori ….develop severe stomach inflammation (gastritis)…lead to ulcers or cancer….causes oxidative stress….creation of carcinogenic chemicals, damage to cellular DNA and growth of cancer cells…… Inflammation severity is affected by strain of bacteria, genetics, lifestyle, dietary factors….smoking….salty foods…. Dietary changes….illiminate salt, green tea, eating lots of green and yellow veggies.. Esophageal Cancer….long-term inflammation due to gastroesophegeal reflux (back up of stomach acids into the esophagus)….alcohol, smoking, scalding hot teas…. Lung Cancer ….study …women who took aspirin 3 or more times a week for 6 months decreased risk….. Breast Cancer ….NSAIDs ….women with rheumatoid arthritis…decreased risk of breast cancer….block the creation of prostaglandins…… Breast Cancer and Colon Cancer….occur in the same patient more often than predicted by statistical chance….western lifestyle, diet, obesity…. Ovarian Cancer ….NSAIDs – reduces the risk Fatigue, Obesity, Depression, Sleep Disorders Part of many medical mysteries: cancer, multiple sclerosis, rheumatoid arthritis, lupus, auto-immune diseases….infections, allergies….link to all these diseases is inflammation….. Sick buildings: irritant gasses …cause inflammation in upper airway…hidden ……other hidden ….migraine headaches (neurogenic inflammation) 2/3 meet the criteria for chronic fatigue syndrome, viruses, allergies….. viral illnesses…..severe fatigue afterwards- have high levels of pro-inflammatory cytokines interferon-gamma and tumor necrosis factor-alpha in their blood…. CFS……Hyperreaction to the inflammatory chemicals produced in their bodies…. 3 possible reasons for fatigue: obesity, depression, and insomnia…..closely related….a number of disease are related to these 3 in a diverse way….inflammation may be the link….. Obesity….inflammatory condition…raises the level of pro-inflammatory chemicals…2 types…..1. gynoid obesity and 2. android obesity Gynoid obesity – shaped like a pear…..more fat on hips than waist..more common in women around menopause Android obesity – shaped like an apple…more fat on waist than hips….beer gut… Physician’s measure is the waist-to-hip ratio. (divide your waist by hip: if number is less than .75 you are gynoid….greater than .85 you have android fat distribution…. Apple shaped women ….greater levels of inflammation …greater risk of blood clots, stroke, and heart disease….. Pg 66…. Fat – excretes pro-inflammatory cytokines…tumor necrosis factor-alpha is secreted by fat cells…. Metabolic syndrome….syndrome x…abdominal obestity, high blood pressure, high blood sugar, elevated cholesterol, elevated triglycerides….. 3 or more… Abdominal obesity – women 35 inches Elevated triglycerides in blood – 160 mg/dL High blood pressure – more than 130/85 Hg High fasting glucose – 110 mg/dL Obesity and inflammation run together……fat itself increases inflammation…??? Does inflammation lead to obesity?????….people who work in sick buildings gain weight…if sources of inflammation are illiminated, losing weight might be easier…. Depression: …….real physical disorders…brain malfunctions…allergies,autoimmune diseases, lupus, multiple sclerosis, etc Sleep Disorders: extensions of inflammations disorders, fatigue, depression, weight issures… Autoimmune Diseases, Allergies, Asthma Inflammation that look and feel like allergy can be caused by stimulation of nerves in the airway….reactions called irritant, or chemical sensitivity….smoke, perfume, cleaning products, solvents…allergies cause an itchy nose, while irritants are more likely to cause a burning sensation… Asthma: type of bronchitis triggered in people susceptible to pollutants, cold dry air, emotional stress, …….. ****Inflammation of the eyes is so common in individuals working in sick buildings in which irritant fumes are present that the term office eye syndrome is used…… Chemical Hypothesis: allergies to cedar tree pollen was rare before the 1950s but is common now….appeared when auto introduced….. Numerous reports….chronic asthma and rhinosinusitis that began with exposure to any of a number of respiratory irritants…inflammation leads to release of a protein called nerve growth factor…grows new sensory nerve ending to respond to irritants….become hypersensitive….. Viral Hypothesis…. Hygiene Hypothesis (Adaptation Hypothesis) Certain foods ….high fat, deep-fried foods…..are related to asthma….as is obesity…. Visable Inflammation: The skin……2 main ways other than germs that can inflame skin….1. an immune response 2. an irritant response…

  2. 5 out of 5

    Msimone

    This is a too général overview of the very many causes and conséquences of inflammation on the body for the reader to cogitate over which include diet, lifestyle, genetic propension, psychological state, age, environment, and disease and presciption drugs. The clinical studies and patient/ doctor case experiences both confirm and deny the corrélation of inflammation with disease. The ultimate takeaway from the book for the reader is that inflammation from many sources can attack the human body t This is a too général overview of the very many causes and conséquences of inflammation on the body for the reader to cogitate over which include diet, lifestyle, genetic propension, psychological state, age, environment, and disease and presciption drugs. The clinical studies and patient/ doctor case experiences both confirm and deny the corrélation of inflammation with disease. The ultimate takeaway from the book for the reader is that inflammation from many sources can attack the human body to diminish lifespan and life quality of everyone, and that each of us need to minimize its noxious effects through self-care and medical consultation. If you are looking for lifestyle advice to improve an inflammatory- related disease that provides specific diet, or exercice recommandations look elsewhere.

  3. 4 out of 5

    Marjan

    Really nice book that can help you get your health in shape. I expected some more detailed medical explanations on the topic of inflammation itself, but on the other hand the author presents a much broader view on the problem (including nutrition, lifestyle and healthy architecture tips). One important thing is missing though, and that is the role of electro-magnetic fields (EMF) and radiation. We are constantly bombarded with EMF from our cell phones, computers, power station, wifi networks, TV Really nice book that can help you get your health in shape. I expected some more detailed medical explanations on the topic of inflammation itself, but on the other hand the author presents a much broader view on the problem (including nutrition, lifestyle and healthy architecture tips). One important thing is missing though, and that is the role of electro-magnetic fields (EMF) and radiation. We are constantly bombarded with EMF from our cell phones, computers, power station, wifi networks, TV's and even kitchen appliances. On top of it many of us have to deal with nuclear radiation from all sorts of radioactive sources which are becoming global by means of atmospheric winds and oceanic currents. Not everything in biology is chemical and this part was sadly forgotten by the author. But the rest is amazing. Strongly recommended for anyone, and it certainly wouldn't hurt if some architects took a peak at it.

  4. 4 out of 5

    Rebecca

    Good book! From the many "cure" books I have read over th years, I feel this one was the least biased, and presented reasonable ideas for individuals with chronic inflammation to try. I was leery about the title of the book, but I appreciate that the material presented does not tout a cure, nor suggest drastic cleansing rituals need to be taken to purge the body. It fundamentally recognizes the biology associated with chronic illness. Overall, a very helpful book for those interested or dealing Good book! From the many "cure" books I have read over th years, I feel this one was the least biased, and presented reasonable ideas for individuals with chronic inflammation to try. I was leery about the title of the book, but I appreciate that the material presented does not tout a cure, nor suggest drastic cleansing rituals need to be taken to purge the body. It fundamentally recognizes the biology associated with chronic illness. Overall, a very helpful book for those interested or dealing with chronic inflammation.

  5. 5 out of 5

    Laurel Bradshaw

    Aside from the very misleading title, this is a solid, informative book. Comprehensive, but nothing new. Very common sense advice which could have been summed up far more succinctly, but if you know nothing on the subject it will give you a good general background. Book description: In clear, everyday language, William Meggs, M.D., explains what causes inflammation, its relationship to disease in the body, and what steps readers can take to minimize their risk.

  6. 4 out of 5

    Marilyn

    What can I say? I'm dealing with a bout of bursitis...The book was fair. Basically, it tells you stuff you already know: Eat right, lose weight, don't smoke, don't drink too much...But I am going to take Dr. Meggs's advice as far as taking certain vitamin and mineral supplements to minimize if not eliminate inflammation. What can I say? I'm dealing with a bout of bursitis...The book was fair. Basically, it tells you stuff you already know: Eat right, lose weight, don't smoke, don't drink too much...But I am going to take Dr. Meggs's advice as far as taking certain vitamin and mineral supplements to minimize if not eliminate inflammation.

  7. 4 out of 5

    Sheryl

    full of very interesting and useful information. Well laid out and easy to understand. I checked this out of the library but will purchase a copy of the ebook for myself.

  8. 4 out of 5

    Sue Lipton

    Pretty good, for a mainstream book.

  9. 5 out of 5

    Kira

  10. 4 out of 5

    Christina

  11. 5 out of 5

    Katherine

    Wonderfully informative!

  12. 5 out of 5

    Al

  13. 4 out of 5

    Terry Weingart

  14. 5 out of 5

    Nancy West

  15. 4 out of 5

    Riddlers Gift

  16. 4 out of 5

    Mary M Adamson

  17. 5 out of 5

    David Cosentino

  18. 4 out of 5

    HelloThere

  19. 4 out of 5

    Whitney

  20. 4 out of 5

    Juan

  21. 4 out of 5

    tinamarie-

  22. 4 out of 5

    A. Kuhlii

  23. 5 out of 5

    Susan

  24. 4 out of 5

    Heather Cryer

  25. 4 out of 5

    Christopher Prosser

  26. 5 out of 5

    Cws

    616.04 Meg

  27. 4 out of 5

    Ann

  28. 5 out of 5

    Rohanknitter

  29. 4 out of 5

    Robert Gulbahce

  30. 4 out of 5

    Mary

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